This prophetic divine judgment on "the woman" (required because of Eve's disobedience to the Word of God) is the first of the Bible's "three sixteens." In contrast, note the promised blessing in the last "three sixteen" of the Old Testament: "Then they that feared the LORD spake often one to another: and the LORD hearkened, and heard it, and a book of remembrance was written before him for them that feared the LORD, and that thought upon his name" (Malachi 3:16).
But look also at some of the "three sixteens" of the New Testament. "And without controversy great is the mystery of godliness: God was manifest in the flesh, justified in the Spirit, seen of angels, preached unto the Gentiles, believed on in the world, received up into glory" (1 Timothy 3:16). Then, consider 2 Timothy 3:16! "All Scripture is given by inspiration of God, and is profitable for doctrine, for reproof, for correction, for instruction in righteousness."
From the inspired Word, we are soon led to seek the indwelling Word. "Let the word of Christ dwell in you richly in all wisdom; teaching and admonishing one another in psalms and hymns and spiritual songs, singing with grace in your hearts to the Lord" (Colossians 3:16). This truth also implies the indwelling Holy Spirit. "Know ye not that ye are the temple of God, and that the Spirit of God dwelleth in you?" (1 Corinthians 3:16).
But when Christians hear the words "three sixteen," most all of us think immediately of these glorious words: "For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life" (John 3:16). HMM http://www.icr.org/articles/type/6/